mRNA is transcribed from DNA (as pre-mRNA in eukaryotes) and processed into mature mRNA before translation.
Messenger RNA (mRNA) is a single-stranded RNA molecule that carries the genetic information of a gene and is read by ribosomes to synthesize proteins. mRNA is produced during transcription, when RNA polymerase copies DNA into a primary transcript called pre-mRNA (especially in eukaryotes). Pre-mRNA is then processed—commonly by removing introns through splicing, adding a 5' cap, and adding a 3' poly(A) tail—to form mature mRNA. In protein synthesis, mature mRNA is translated by ribosomes. The nucleotide sequence is organized into codons (three nucleotides each), where each codon specifies an amino acid or signals termination via stop codons. Translation uses transfer RNA (tRNA) to match codons with amino acids and ribosomal RNA (rRNA) as part of the ribosome’s protein-manufacturing machinery. Thus, mRNA serves as the key intermediary between genetic information in nucleic acids and the final protein product, linking transcription to translation within the central dogma.
mRNA is transcribed from DNA (as pre-mRNA in eukaryotes) and processed into mature mRNA before translation.
During translation, ribosomes read mRNA codons to build a protein using amino acids supplied by tRNA, with stop codons ending synthesis.
A single-stranded RNA molecule whose nucleotide sequence corresponds to a gene and is read by ribosomes to synthesize a protein.
The initial RNA transcript produced during transcription that often contains introns and must be processed to become mature mRNA.
The process that removes non-coding introns from pre-mRNA and joins exons to form mature mRNA.
A modified guanine nucleotide added to the 5' end of eukaryotic mRNA that helps ribosome recognition and protects the RNA from degradation.
A stretch of adenine nucleotides added to the 3' end of eukaryotic mRNA that promotes stability, export, and translation.
A sequence of three nucleotides in mRNA that specifies an amino acid or a stop signal during translation.
The process by which ribosomes read mRNA codons and assemble the corresponding protein using amino acids carried by tRNA.
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