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Common sepsis symptoms include fever or low temperature, fast heart rate, fast breathing, confusion, and sometimes edema; symptoms may also match the source of infection.
Sepsis is a life-threatening condition caused by the body’s dysregulated response to an infection. Common signs and symptoms include fever, low body temperature, rapid heart rate, rapid breathing, confusion, and swelling (edema). Symptoms may also reflect the underlying infection (for example, cough with pneumonia or painful urination with a kidney infection). In very young, older, or immunocompromised people, fever may be absent and body temperature may be low or normal. Early sepsis may present with fast heart rate, decreased urination, and high blood sugar. As sepsis becomes established or severe, it can lead to organ dysfunction and reduced blood flow, which may show up as low blood pressure, metabolic acidosis (often with faster breathing), worsening mental status, and problems with blood clotting that can progress to organ failure. Low blood pressure that does not improve after fluid replacement, or that requires medications to maintain blood pressure, is characteristic of septic shock.
Common sepsis symptoms include fever or low temperature, fast heart rate, fast breathing, confusion, and sometimes edema; symptoms may also match the source of infection.
Sepsis can progress to organ dysfunction, suggested by low blood pressure, high lactate/poor perfusion indicators (such as low urine output), metabolic acidosis, and clotting abnormalities that may lead to organ failure.
Septic shock is defined by persistent low blood pressure due to sepsis that does not improve with fluids or requires vasopressors to maintain blood pressure.
A potentially life-threatening condition where the body’s dysregulated response to infection causes injury to its own tissues and organs.
A form of sepsis with low blood pressure that persists despite fluid replacement or requires medications (vasopressors) to maintain blood pressure.
An acid–base disturbance that can occur in sepsis and may be accompanied by faster breathing as the body attempts to compensate.
Impairment of one or more organ systems due to sepsis, which can progress to multiple organ failure.
Reduced blood flow to tissues, suggested by findings such as low urine output and elevated lactate in sepsis.
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